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Minneapolis VA Health Care System Research Service
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Investigator Profile
Minneapolis VA Health Care System Research Service
Investigator Profile
Christine Wendt, MD
- Positions
- Section Chief, Pulmonary, Allergy, Critical Care and Sleep, Minneapolis VA
Professor of Medicine, University of Minnesota - Education
- BS, MD University of Minnesota
- Contact Information
- christine.wendt@va.gov
- Research Interests
- I am a Professor of Medicine and Section Chief of Pulmonary, Allergy, Critical Care, and Sleep (PACCS) at the Minneapolis VAMC. Our section is a national leader in COPD research. My research has focused on both clinical and translational research in COPD and associated contributors including tobacco, HIV, air pollution and COPD as a causal pathway to lung cancer. For my translational research using a multi-omic approach including genomics, transcriptomics, proteomics, metabolomics, computational and systems biology I have identified biomarkers and causal pathways in COPD leading to lung cancer and HIV-associated COPD. I have participated on five large NIH COPD trials, including the NIH COPD Clinical Research Network and the VA Lung Precision Oncology Program. I have also directed a pilot RCT to explore the role of the microbiome in COPD exacerbations and symptoms. My interest in air pollution and chronic lung disease dates to my participation as a delegate for the University of Minnesota and Chinese Academy of Science to address the health effects of air pollution in China. I have extended this area of research to include epidemiology and respiratory effects of deployment-related air pollution exposure, including burn pit exposure. My research has focused on biomarkers of disease using high-throughput mass spectrometry, specifically focusing on chronic obstructive lung diseases. I have a long-standing interest in clinical and translational research in COPD.
- Publications
- Full bibliography on PubMed
- VA Research Topics
- Respiration & Pulmonary Disease;
- Cancer
- MeSH Key Words
- Proteomics; Metabolomics; Biomarkers; Pulmonary Disease, Chronic Obstructive; Lung Neoplasms; Air Pollution; Lung Diseases; Microbiota; HIV Infections
- Professional Networking
- ORCID | Google Scholar
- Links
- University of Minnesota profile